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Non-Small Cell Lung Cancer

Research from S. Alsaad et al broadens understanding of non-small cell lung cancer

Published in Cancer Weekly, December 29th, 2009

According to recent research from Norway, "By tissue microarray methodology, the expression of altered Akt isoforms, PTEN and PI3K and their prognostic significance in 335 non-small cell lung cancer (NSCLC) tumors were investigated. Tumor tissue was sampled and immunohistochemicaly quantified in 335 tumors from stage I to IIIA NSCLC patients both from tumor epithelial cells and surrounding stromal tissue in resected specimens."

"Correlations were made with clinicopathological variables. In addition, the expression of these markers was compared to 20 lung tissue cores from patients without any history of malignancy. A significantly higher PTEN expression was observed in...

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