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Colon Cancer

New colon cancer research from Kanazawa University discussed

Published in Cancer Weekly, January 5th, 2010

"Glycogen synthase kinase-3 beta (GSK3 beta) regulates multiple cell signaling pathways and has been implicated in glucose intolerance, neurodegenerative disorders, and inflammation. We investigated the expression, activity, and putative pathologic role of GSK3 beta in gastrointestinal, pancreatic, and liver cancers," scientists in Kanazawa, Japan report.

"Colon, stomach, pancreatic, and liver cancer cell lines; nonneoplastic HEK293 cells; and matched pairs of normal and tumor tissues of stomach and colon cancer patients were examined for GSK3 beta expression and its phosphorylation at serine 9 (inactive form) and tyrosine 216 (active form) by Western immunoblotting and...

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