Cancer Gene Therapy
National Cheng-Kung University, Institute of Clinical Medicine details research in cancer gene therapy
Published in Cancer Weekly, January 5th, 2010
A report, 'Enhancement of antitumor activity of gammaretrovirus carrying IL-12 gene through genetic modification of envelope targeting HER2 receptor: a promising strategy for bladder cancer therapy,' is newly published data in Cancer Gene Therapy. "The objective of this study was to develop an HER2-targeted, envelope-modified Moloney murine leukemia virus (MoMLV)-based gammaretroviral vector carrying interleukin (IL)-12 gene for bladder cancer therapy. It displayed a chimeric envelope protein containing a single-chain variable fragment (scFv) antibody to the HER2 receptor and carried the mouse IL-12 gene," researchers in Tainan, Taiwan report.
"The fragment of...
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Source: Cancer Weekly (2010-01-05)
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