Urokinase Therapy
Research from X.L. Cheng et al has provided new information about urokinase therapy
Published in Cancer Weekly, January 5th, 2010
"However, the mechanism by which ECRG2 performs these activities is a compelling question. Urokinase-type plasmin activator (uPA) binding to uPAR induces migration/invasion through multiple interactors including integrins. In this study, we found that ECRG2 binds specifically to the kringle domain of uPA. Moreover, we demonstrated that ECRG2 forms a complex with uPA.uPAR, that such a complex modifies the dynamical...
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Source: Cancer Weekly (2010-01-05)
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