Gene Therapy
Studies from University of Edinburgh, Queen's Medical Research Institute provide new data on gene therapy
Published in Cancer Weekly, January 5th, 2010
Data detailed in 'Integrin activation by Fam38A uses a novel mechanism of R-Ras targeting to the endoplasmic reticulum' have been presented. "The integrin family of heterodimeric cell-surface receptors are fundamental in cell-cell and cell-matrix adhesion. Changes to either integrin-ligand affinity or integrin gene expression are central to a variety of disease processes, including inflammation, cardiovascular disease and cancer," scientists writing in the journal Development report.
"In screening for novel activators of integrin-ligand affinity we identified the previously uncharacterised multi-transmembrane domain protein Fam38A, located at the endoplasmic...
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Source: Cancer Weekly (2010-01-05)
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