Life Sciences
Scientists at National Cancer Center detail research in life sciences
Published in Cancer Weekly, January 5th, 2010
Researchers detail in 'HIF-1 is induced via EGFR activation and mediates resistance to anoikis-like cell death under lipid rafts/caveolae-disrupting stress,' new data in life sciences. According to recent research from Korea, "The plasma membrane microdomains, lipid rafts, are involved in regulation of cellular functions such as cell survival and adhesion. Cholesterol is a critical component of lipid rafts in terms of their integrity and functions and rafts disruption by cholesterol depletion can induce detachment-induced cell death."
"Hypoxia inducible factor-1 (HIF-1) alpha is stabilized in hypoxia and transactivates numerous genes required for cellular adaptation to...
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Source: Cancer Weekly (2010-01-05)
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