Journal of the National Cancer Institute
High risk of colorectal, endometrial and Lynch syndrome cancers for MSH6 mutation carriers
Published in Cancer Weekly, January 5th, 2010
It is known that mutations in MSH6 account for 10%-20% of Lynch syndrome, which causes colorectal and other cancers, but less is know about the cumulative cancer risks for mutation carriers.
In this study, members of the Colon Cancer Family Registry, a National Institutes of Health-funded consortium, and colleagues identified 113 families of MSH6 mutation carriers from five countries who...
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Source: Cancer Weekly (2010-01-05)
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