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Cancer Epidemiology

Report summarizes cancer epidemiology study findings from J.E. Muscat and co-researchers

Published in Cancer Weekly, January 26th, 2010

"There is wide variability in cotinine levels per cigarette smoked. We hypothesized that in addition to smoking frequency, other behavioral measures of nicotine dependence, such as the time to first cigarette after waking, are associated with cotinine levels," scientists in the United States report.

"To test this hypothesis, we measured plasma and urinary cotinine in a community-based study of 252 black and white daily cigarette smokers. Among one pack per day smokers, plasma cotinine levels varied from 16 to 1,180 ng/mL, a 74-fold difference. Two nicotine dependence phenotypes were discerned by time after waking. in the ''low'' dependent phenotype smoked >30 minutes...

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