Published in Cancer Weekly, January 26th, 2010
"We investigated the activation of these enzymes by differing DNA ends and their interaction in the cellular response to ionizing radiation (IR). The effect of PARP and DNA-PK inhibitors (KU-0058684 and NU7441) on repair of IR-induced DSBs was investigated in DNA-PK and PARP-1 proficient and deficient cells by measuring gamma H2AX foci...
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