Laryngeal Cancer

Data on laryngeal cancer published by researchers at Zhejiang University

Published in Cancer Weekly, January 26th, 2010

"Malignant cells show increased glucose uptake in vitro and in vivo, which is thought to be mediated by glucose transporters. In this study, we investigated the effect of plasmid-derived antisense RNA against the Glut-I gene on proliferation and glucose uptake in laryngeal carcinoma Hep-2 cells," scientists writing in the Head and Neck - Journal for the Sciences and Specialties of the Head and Neck report.

"The expression plasmids pcDNA3.1(+)-Glut-1 and pcDNA3. 1(+)-anti Glut-1 were constructed. The MTT method was used to assess cell growth inhibition. The expression of Glut-1 mRNA and protein was detected by reverse transcriptase-polymerase chain reaction and...

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Source: Cancer Weekly (2010-01-26)

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