Nerve Sheath Tumors

New nerve sheath tumors study findings have been reported from M. Hakozaki et al

Published in Cancer Weekly, January 26th, 2010

"Malignant peripheral nerve sheath tumor (MPNST) is a rare soft tissue sarcoma. We established a new human MPNST cell line (designated FMS-1) from MPNST of the right brachial plexus of a 69-year-old woman with NF1," scientists in Fukushima, Japan report.

"The cell line has been maintained for > 24 months with > 100 passages. FMS-1 cells showed a fibrosarcoma-like or epithelioid pattern in the heterotransplanted tumor, compared with a fascicular growth pattern of short-spindle tumor cells in the primary tumor. Immunophenotypically, FMS-1 cells showed almost the same characteristics as the primary tumor. Cytogenetic and molecular analyses revealed a deletion in...

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Source: Cancer Weekly (2010-01-26)

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