Nerve Sheath Tumors
Research results from Brigham and Women's Hospital update understanding of nerve sheath tumors
Published in Cancer Weekly, January 26th, 2010
According to a study from the United States, "Smoothelin is a smooth muscle-specific cytoskeletal protein exclusively found in differentiated smooth muscle cells. This contrasts with other smooth muscle proteins (eg, h-caldesmon, alpha-smooth Muscle actin, desmin, Smooth muscle myosin), which are expressed in proliferative (early) stages of smooth muscle development and occasionally in other cell types (striated muscle, myofibroblasts, myoepithelial cells, pericytes)."
"Smoothelin has been shown to be expressed predominantly in visceral smooth muscle and to a lesser extent in vascular smooth muscle. Smoothelin expression in mesenchymal tumors of the gastrointestinal...
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Source: Cancer Weekly (2010-01-26)
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