Lymphoma Genetics
Research reports on lymphoma genetics from Yale University, Yale Cancer Center provide new insights
Published in Cancer Weekly, February 2nd, 2010
Data detailed in 'EBNA1 regulates cellular gene expression by binding cellular promoters' have been presented. According to a study from the United States, "Epstein-Barr virus (EBV) is associated with several types of lymphomas and epithelial tumors including Burkitt's lymphoma (BL), HIV-associated lymphoma, posttransplant lymphoproliferative disorder, and nasopharyngeal carcinoma. EBV nuclear antigen 1 (EBNA1) is expressed in all EBV associated tumors and is required for latency and transformation."
"EBNA1 initiates latent viral replication in B cells, maintains the viral genome copy number, and regulates transcription of other EBV-encoded latent genes. These...
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Source: Cancer Weekly (2010-02-02)
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