Breast Cancer

New breast cancer findings from University of Barcelona described

Published in Cancer Weekly, February 2nd, 2010

According to a study from Barcelona, Spain, "The aim of this study is to evaluate the impact of CYP2D6 genotyping in predicting disease-free survival and toxicity in breast cancer patients treated with adjuvant tamoxifen. DNA from 91 patients was genotyped using the AmpliChip CYP450 GeneChip(A ®), Roche that facilitates the classification of individuals by testing 27 alleles."

"When patients were grouped into group 1 (*4/*4, *4/*41, *1/*5 and *2/*5) and group 2 (the remaining genotypes), a significant difference in disease-free survival (DFS) was observed between groups (P = 0.016). The mean DFS in group 1 was 95 months in contrast with 119 months in group 2. No...

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Source: Cancer Weekly (2010-02-02)

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