Neuroblastoma
Researchers at Hokkaido University have published new data on neuroblastoma
Published in Cancer Weekly, February 2nd, 2010
Investigators publish new data in the report 'Cell density-dependent increase in the level of protease-resistant prion protein in prion-infected Neuro2a mouse neuroblastoma cells.' "Cells persistently infected with prions continuously produce protease-resistant prion protein (PrP-res). Here, we show that the PrP-res level in prion-infected Neuro2a (N2a) neuroblastoma cells decreased to 50% of their initial level over the first 48 h and then recovered by 96 h after seeding," researchers in Sapporo, Japan report.
"The level of cellular prion protein (PrP(C)) also appeared to fluctuate, but did not influence the fluctuation of the PrP-res level. Prion-infected N2a cells,...
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Source: Cancer Weekly (2010-02-02)
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