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Neuroblastoma Cell Biology

Research reports on neuroblastoma cell biology from Nancy University provide new insights

Published in Cancer Weekly, February 2nd, 2010

Investigators publish new data in the report 'Vitamin B12 deficiency reduces proliferation and promotes differentiation of neuroblastoma cells and up-regulates PP2A, proNGF, and TACE.' According to recent research published in the journal Proceedings of the National Academy of Sciences of the United States of America, "Vitamin B12 (cobalamin, Cbl) is indispensable for proper brain development and functioning, suggesting that it has neurotrophic effects beside its well-known importance in metabolism. The molecular basis of these effects remains hypothetical, one of the reasons being that no efficient cell model has been made available for investigating the consequences of B12...

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