Vascular Endothelial Growth Factor
New vascular endothelial growth factor findings from C. Maes and co-authors described
Published in Cancer Weekly, February 2nd, 2010
Current study results from the report, 'Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones,' have been published. According to recent research published in the The EMBO Journal, "Vascular endothelial growth factor (VEGF) and beta-catenin both act broadly in embryogenesis and adulthood, including in the skeletal and vascular systems. Increased or deregulated activity of these molecules has been linked to cancer and bone-related pathologies."
"By using novel mouse models to locally increase VEGF levels in the skeleton, we found that embryonic VEGF over-expression in osteo-chondroprogenitors and their progeny largely...
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Source: Cancer Weekly (2010-02-02)
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