Adenocarcinoma

Data from Brown University advance knowledge in adenocarcinoma

Published in Cancer Weekly, February 2nd, 2010

"Gross cystic disease fluid protein (GCDFP-15) is currently used as an immunohistochemical marker of breast cancer, whereas thyroid transcription factor (TTF-1) is commonly used as a marker of primary lung neoplasms. Traditionally, a GCDFP-15+/TTF-1 - immunohistochemical profile in lung tumors has been considered as highly Suggestive of metastatic carcinoma of the breast," scientists in the United States report.

"Here, we investigated the expression of GCDFP-15 and TTF-1 on a tissue microarray consisting of 381 primary lung carcinomas. GCDFP-15 was expressed in normal bronchial submucosal glands and bronchial epithelium, which were negative for TTF-1. Seventeen tumors...

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Source: Cancer Weekly (2010-02-02)

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