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Urothelial Cancer

Data on urothelial cancer reported by researchers at Mayo Clinic

Published in Cancer Weekly, February 2nd, 2010

"Urothelial carcinoma develops from a diffusely susceptible mucosa and, thus, patients who undergo cystectomy are at risk for upper tract recurrence. Management of the distal ureter at cystectomy remains controversial and the impact of a sequential sectioning strategy remains unclear," investigators in the United States report.

"We identified 1,397 patients who underwent radical cystectomy for nonmetastatic urothelial carcinoma from 1980 to 1998. All patients underwent frozen section analysis of the distal ureteral specimen. When positive, additional specimens were. obtained. We evaluated the impact of a positive ureteral margin and the effect of ultimately obtaining a...

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