Bioengineering
Investigators at University of Mississippi Medical Center, Department of Biochemistry release new data on bioengineering
Published in Cancer Weekly, February 2nd, 2010
Data detailed in 'Inhibition of ovarian cancer cell proliferation by a cell cycle inhibitory peptide fused to a thermally responsive polypeptide carrier' have been presented. According to recent research from the United States, "Current treatment of solid tumors is limited by normal tissue tolerance, resulting in a narrow therapeutic index. To increase drug specificity and efficacy and to reduce toxicity in normal tissues, we have developed a polypeptide carrier for a cell cycle inhibitory peptide, which has the potential to be thermally targeted to the tumor site."
"The design of this polypeptide is based on elastin-like polypeptide (ELP). The coding sequence of ELP...
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Source: Cancer Weekly (2010-02-02)
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