Breast Cancer Therapy
Studies conducted at Indiana University, Department of Surgery on breast cancer therapy recently published
Published in Cancer Weekly, February 2nd, 2010
Fresh data on breast cancer are presented in the report 'Prognosis of hormone-dependent breast cancers: implications of the presence of dysfunctional transcriptional networks activated by insulin via the immune transcription factor T-bet.' "Estrogen receptor alpha (ERalpha)-positive breast cancers that co-express transcription factors GATA-3 and FOXA1 have a favorable prognosis. These transcription factors form an autoregulatory hormonal network that influences estrogen responsiveness and sensitivity to hormonal therapy," researchers in the United States report.
"Disruption of this network may be a mechanism whereby ERalpha-positive breast cancers become resistant to...
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Source: Cancer Weekly (2010-02-02)
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