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Erlotinib Therapy

Reports on erlotinib therapy findings from Roswell Park Cancer Institute provide new insights

Published in Cancer Weekly, February 9th, 2010

Research findings, 'A review of erlotinib--an oral, selective epidermal growth factor receptor tyrosine kinase inhibitor,' are discussed in a new report. According to recent research from the United States, "IMPORTANCE OF THE FIELD: The epidermal growth factor receptor (EGFR) is a cell surface receptor for EGF and transforming growth factor-alpha which is overexpressed by a number of human tumors. Erlotinib, developed by OSI Pharmaceuticals, is an oral selective EGFR tyrosine kinase inhibitor, the only drug of its class approved for the treatment of locally advanced non-small cell lung cancer (NSCLC) after failure of at least one previous chemotherapy regimen and for first-line treatment...

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