Published in Cancer Weekly, February 9th, 2010
"Sorafenib reduces tumor perfusion and thereby induces necrosis and often hemorrhage. Malignant tumors treated with sorafenib undergo both morphologic and functional changes; however, the morphologic changes are less frequent and inadequate for early evaluation of response," wrote O. Maksimovic and colleagues, University of Tubingen.
The researchers concluded: "Therefore, imaging tools accurately assessing hemorrhage and decrease in tumor perfusion...
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