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Myeloma

Research on myeloma discussed by scientists at University of Athens

Published in Cancer Weekly, February 9th, 2010

In this recent study, researchers in Athens, Greece conducted a study "To assess bortezomib plus melphalan and prednisone (VMP) and melphalan and prednisone (MP) in previously untreated patients with multiple myeloma (MM) with renal impairment enrolled on the phase III VISTA study, and to evaluate renal impairment reversibility. Patients received nine 6-week cycles of VMP (bortezomib 1.3 mg/m(2), melphalan 9 mg/m(2), prednisone 60 mg/m(2)) or MP."

"with serum creatinine higher than 2 mg/dL were excluded. In the VMP/MP arms, 6%/4%, 27%/30%, and 67%/66% of patients had baseline glomerular filtration rate (GFR) of <= 30, 31 to 50, and higher than 50 mL/min,...

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