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Breast Cancer Risk Factors

Research on breast cancer risk factors described by scientists at Roswell Park Cancer Institute

Published in Cancer Weekly, February 23rd, 2010

Data detailed in 'Mitochondrial copy number and risk of breast cancer: a pilot study' have been presented. "It has been proposed that the copy number of mitochondria DNA (mtDNA) per cell reflects gene-environment interactions between unknown hereditary factors and exposures affecting levels of oxidative stress. However, whether copy number of mtDNA could be a risk predictor of oxidative stress-related human cancers, such as breast cancer, remains to be determined," scientists in the United States report.

"To explore the role of mtDNA copy number in breast cancer etiology, we analyzed mtDNA copy number in whole blood from 103 patients with breast cancer and 103 matched...

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