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Oral Squamous Cell Carcinoma

Data on oral squamous cell carcinoma reported by S. Ohba and co-researchers

Published in Cancer Weekly, March 2nd, 2010

"Malignant cells show increased uptake, which is considered to be facilitated by glucose transporters (GLUTs). Increased GLUT-1 expression has been reported in many human cancers," researchers in Tokyo, Japan report.

"We hypothesized that a oral squamous cell carcinoma, characterized by high frequency of lymph node metastasis, distant metastasis or local recurrences, was associated with GLUT-1 overexpression in invasion front. GLUT-1 immunostaining in invasion front was studied on 24 oral squamous cell carcinomas, and revealed the correlation with the clinical characteristics. The analysis showed that all oral squamous cell carcinoma patients and GLUT-1 expression...

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