Breast Cancer
Researchers from Mayo Clinic College of Medicine, Department of Anesthesiology report recent findings in breast cancer
Published in Cancer Weekly, March 2nd, 2010
A report, 'Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice,' is newly published data in The Journal of Clinical Investigation. According to a study from the United States, "The enzyme sirtuin 1 (SIRT1) is a critical regulator of many cellular functions, including energy metabolism. However, the precise mechanisms that modulate SIRT1 activity remain unknown."
"As SIRT1 activity in vitro was recently found to be negatively regulated by interaction with the deleted in breast cancer-1 (DBC1) protein, we set out to investigate whether DBC1 regulates SIRT1 activity in vivo. We found that DBC1 and...
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Source: Cancer Weekly (2010-03-02)
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