Breast Cancer Therapy
Study findings from J.R Pasqualini et al broaden understanding of breast cancer therapy
Published in Cancer Weekly, March 2nd, 2010
New research, 'Breast cancer and steroid metabolizing enzymes: the role of progestogens,' is the subject of a report. "It is well documented that breast tissue, both normal and cancerous, contains all the enzymatic systems necessary for the bioformation and metabolic transformation of estrogens, androgens and progesterone. These include sulfatases, aromatase, hydroxysteroid-dehydrogenases, sulfotransferases, hydroxylases and glucuronidases," investigators in Paris, France report.
"The control of these enzymes plays an important role in the development and pathogenesis of hormone-dependent breast cancer. As discussed in this review, various progestogens including...
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Source: Cancer Weekly (2010-03-02)
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