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Cancer Gene Therapy

Research from University of Southern California, Norris Comprehensive Cancer Center yields new data on cancer gene therapy

Published in Cancer Weekly, March 9th, 2010

New investigation results, 'Reprogramming murine telomerase rapidly inhibits the growth of mouse cancer cells in vitro and in vivo,' are detailed in a study published in Molecular Cancer Therapeutics. According to recent research published in the journal Molecular Cancer Therapeutics, "Telomerase plays a critical role in cancer, prompting the pursuit of various telomerase-based therapeutic strategies. One such strategy, telomerase interference, exploits the high telomerase activity in cancer cells and reprograms telomerase to encode 'toxic' telomeres."

"To date, telomerase interference has been tested in human cancer cells xenografted into mice, an...

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