Cold Spring Harbor Laboratory

Melanoma transcriptome reveals novel genomic alterations not seen before

Published in Cancer Weekly, March 9th, 2010

Melanoma, the most deadly form of skin cancer, afflicts more than 50,000 people in the United States annually and the incidence rate continues to rise. In a study published online in Genome Research (www.genome.org), scientists have delved deeper than ever before into the RNA world of the melanoma tumor and identified genomic alterations that could play a role in the disease.

The latest high-throughput DNA sequencing technologies are ushering in a new era of discovery in cancer genomics that promises to reveal molecular mechanisms of the disease. Beyond cataloging the genetic mutations present in tumors, application of high-throughput sequencing to the RNA...

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Source: Cancer Weekly (2010-03-09)

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