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Helmholtz Association of German Research Centres

Scientists discover cause of destructive inflammations

Published in Cancer Weekly, March 16th, 2010

The signaling molecule CD95L, known as "death messenger," causes an inflammatory process in injured tissue after spinal cord injuries and prevents its healing. This discovery was published by scientists of the German Cancer Research Center. In mice, the researchers found out that if they switch off CD95L, the injured spinal cord heals and the animals regain better ability to move. Therefore, substances which block the death messenger might offer a new approach in the treatment of severe inflammatory diseases.

A couple of years ago, Dr. Ana Martin-Villalba of the German Cancer Research Center already succeeded in reducing the effects of spinal cord injuries in mice. She...

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