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International Association for the Study of Lung Cancer

Patient age not a factor in use of second-line therapy for lung cancer

Published in Cancer Weekly, March 16th, 2010

Research published in the March issue of the Journal of Thoracic Oncology sought to determine whether differences existed in tolerance and efficacy between patients age 70 and over and younger patients with non-small cell lung cancer (NSCLC) receiving salvage targeted therapy with epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) or chemotherapy.

Lung cancer is the leading cause of cancer death in the world. Lung cancer incidence peaks between ages 70 and 80, and the mortality rate increases with age. EGFR-TKIs, such as getinib or erlotinib, are effective agents used in salvage therapy for NSCLC after patients have failed previous chemotherapy and...

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