Mucositis
Reports summarize mucositis study results from K.L. Tooley and co-researchers
Published in Cancer Weekly, March 30th, 2010
"In order to determine the sensitivity and specificity of the test and to optimize experimental conditions utilizing the SBT in a rat model of chemotherapy-induced small intestinal damage. Initially, a C-13-sucrose dose-response study was performed in rats to determine an optimal sucrose concentration for the SBT; then applied to assess chemotherapy-induced intestinal damage," scientists in Adelaide, Australia report.
"A further study was conducted to establish a SBT time-course of methotrexate-induced small intestinal damage and repair. Animals were killed at 96 or 144 h. A sucrose concentration of 0.25 g/ml was optimal (20% CV) for reproducibility and detection of...
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Source: Cancer Weekly (2010-03-30)
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