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Breast Cancer Genetics

New breast cancer genetics research from University of Pittsburgh, Department of Pathology described

Published in Cancer Weekly, March 30th, 2010

Researchers detail in 'Breast cancer molecular class ERBB2: preponderance of tumors with apocrine differentiation and expression of basal phenotype markers CK5, CK5/6, and EGFR,' new data in breast cancer. According to recent research from the United States, "This is a study of 205 consecutive invasive breast carcinomas. The principal aim was to identify morphologic and immunohistochemical features of tumors that belong to the molecular class ERBB2."

"The invasive breast carcinomas were classified using semiquantitative immunohistochemical results for estrogen receptor (ER), progesterone receptor, (PR), and HER2 into following classes: Luminal A (strong ER+, HER2...

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