Cytometry
Reports on cytometry findings from New York Medical College, Brander Cancer Research Institute provide new insights
Published in Cancer Weekly, March 30th, 2010
A new study, 'Kinetics of the UV-induced DNA damage response in relation to cell cycle phase. Correlation with DNA replication,' is now available. According to a study from the United States, "It has been reported that exposure to UV light triggers DNA damage response (DDR) seen as induction of gammaH2AX not only in S-but also in G(1)-phase cells. In the present study, in addition to gammaH2AX, we assessed other markers of DDR, namely phosphorylation of ATM on Ser1981, of ATM/ATR substrate on Ser/Thr at SQ/TQ cluster domains and of the tumor suppressor p53 on Ser15, in human pulmonary carcinoma A549 cells irradiated with 50 J/m2 of UV-B."
"Phosphorylation of...
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Source: Cancer Weekly (2010-03-30)
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