Lymphoma Genetics
Data from Fudan University, Department of Oncology provide new insights into lymphoma genetics
Published in Cancer Weekly, March 30th, 2010
Research findings, 'Mutations of NFKBIA in biopsy specimens from Hodgkin lymphoma,' are discussed in a new report. "To determine the possible alteration of the inhibitor kappaBalpha (HUGO-approved symbol, NF-kBIA) gene in Chinese Hodgkin lymphoma (HL) patients, NF-kBIA mRNA and protein expression in 22 primary HL patients were examined. Individual tumor cells were used for amplification to obtain the NF-kBIA gene, and the polymerase chain reaction products were sequenced," scientists writing in the journal Cancer Genetics and Cytogenetics report.
"Compared with reactive surrounding lymphocytes, inhibitor kappaBalpha protein (IkappaBalpha) expression was weaker in...
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Source: Cancer Weekly (2010-03-30)
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