Adenocarcinoma Cell Biology
New findings in adenocarcinoma cell biology described from Chosun University, Department of Pathology
Published in Cancer Weekly, April 20th, 2010
New investigation results, '5'-Nitro-indirubinoxime induces G1 cell cycle arrest and apoptosis in salivary gland adenocarcinoma cells through the inhibition of Notch-1 signaling,' are detailed in a study published in Biochimica Et Biophysica Acta. "5'-Nitro-indirubinoxime (5'-NIO) is a new derivative of indirubin that exhibits anti-cancer activity in a variety of human cancer cells. However, its mechanism has not been fully clarified," investigators in Korea report.
"Human salivary gland adenocarcinoma (SGT) cells were used in this study. Western blot and RT-PCR analyses were performed to determine cellular Notch levels. The cell cycle stage and level of...
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Source: Cancer Weekly (2010-04-20)
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