Breast Cancer
Studies from University of Western Ontario, Siebens-Drake Medical Research Institute describe new findings in breast cancer
Published in Cancer Weekly, April 20th, 2010
Fresh data on breast cancer are presented in the report 'NIP1/DUOXA1 expression in epithelial breast cancer cells: regulation of cell adhesion and actin dynamics.' "DUOXA1/NIP1, originally identified as a Numb-interacting protein, was recently shown to function as a maturation factor for the dual oxidase 1(DUOX1). In this study, we identified DUOXA1/NIP1 expression in breast cancer cells, observed high expression of DUOXA1 in non-invasive MCF7 cells and low expression in highly metastatic cells with impaired p53 functions linking the expression of DUOXA1 with p53," investigators in London, Canada report.
"An inhibition of cell proliferation associated with upregulation...
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Source: Cancer Weekly (2010-04-20)
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