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Hepatocellular Cancer

Studies from Sun Yat-Sen University provide new data on hepatocellular cancer

Published in Cancer Weekly, April 20th, 2010

Researchers detail in 'Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma,' new data in hepatocellular cancer. "Based on microarray data, we have previously shown a significant down-regulation of miR-29 in hepatocellular carcinoma (HCC) tissues. To date, the role of miR-29 deregulation in hepatocarcinogenesis and the signaling pathways by which miR-29 exerts its function and modulates the malignant phenotypes of HCC cells remain largely unknown," scientists in People's Republic of China report.

"In this study, we confirmed that reduced expression of miR-29 was a frequent event in HCC tissues using both Northern blot and...

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