Children's Hospital Boston
Cellular Channel May Open Doors to Skin Conditions, Hair Growth
Published in Cancer Weekly, April 27th, 2010
Skin and hair follicles are constantly renewed in the body, maintained by specialized stem cells. New research from Children's Hospital Boston identifies a small cellular channel that regulates skin and hair growth and that could be targeted with small-molecule drugs, potentially treating variety of skin conditions, as well as thinning hair or unwanted hair growth. Findings appear in the April 16 issue of Cell.
Several known factors regulate the growth and specialization of cells in the epidermis. Two key players are transforming growth factor alpha (TGF-alpha) and the receptor for epidermal growth factor (EGFR). Without them, mice have wavy hair; when they are...
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Source: Cancer Weekly (2010-04-27)
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