Squamous Cell Carcinoma

Research on squamous cell carcinoma published by A. Rossini et al

Published in Cancer Weekly, April 27th, 2010

"Esophageal cancer (EC) is among the 10 most common and fatal malignacies in the world, presenting a marked geographic variation in incidence rates between and within different countries. The TP53 tumor suppressor gene is highly mutated in esophageal tumors and its mutation pattern can offer clues to the etiopathology of the tumor," scientists in Brazil report.

"As Brazil presents one of the highest incidence areas in the West, a deeper knowledge of the molecular mechanisms related to EC development in the Brazilian population is needed. We analyzed the mutation profile of 110 esophageal squamous cell carcinomas (ESCC) of patients from Southeastern Brazil (Rio de...

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Source: Cancer Weekly (2010-04-27)

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