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Researchers from Memorial Sloan-Kettering Cancer Center discuss findings in life sciences

Published in Cancer Weekly, May 4th, 2010

Investigators publish new data in the report 'Comparing RNA secondary structures using a relaxed base-pair score.' "The use of free energy-based algorithms to compute RNA secondary structures produces, in general, large numbers of foldings. Recent research has addressed the problem of grouping structures into a small number of clusters and computing a representative folding for each cluster," scientists in the United States report.

"At the heart of this problem is the need to compute a quantity that measures the difference between pairs of foldings. We introduce a new concept, the relaxed base-pair (RBP) score, designed to give a more biologically realistic measure of...

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