Georgetown University Medical Center
Breast cancer risk tied to grandmother's diet
Published in Cancer Weekly, May 4th, 2010
Eating too much fat in pregnancy may be an indulgence that has a less-than-beneficial effect on generations to come, say researchers at Georgetown Lombardi Comprehensive Cancer Center. Their unique study in rats shows that pregnant females that ate a high fat diet not only increased breast cancer risk in their female daughters but also in that daughter's offspring - the "granddaughters." Details of the study will be presented at the AACR 101st Annual Meeting 2010.
The researchers say they don't know why this risk is passed on through two generations, but they believe it occurs through as-yet unknown "epigenetic" changes that result in an increase in terminal end buds in...
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Source: Cancer Weekly (2010-05-04)
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