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New life sciences study results from University of Seville, Research Department described

Published in Cancer Weekly, May 4th, 2010

Research findings, 'Potential role of HDAC inhibitors in cancer therapy: insights into oral squamous cell carcinoma,' are discussed in a new report. "Histone deacetylases (HDACs) are enzymes that are involved in the remodeling of chromatin and play a key role in the epigenetic regulation of gene expression. In addition, the activity of non-histone proteins can be regulated through HDAC-mediated hypoacetylation," scientists in Seville, Spain report.

"In recent years, inhibition of HDACs has emerged as a potential strategy to reverse aberrant epigenetic changes associated with cancer, and several classes of HDAC inhibitors have been found to have potent and specific...

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