Pancreatic Cancer
Researchers from Institute of Chemical Biology and Fundamental Medicine discuss findings in pancreatic cancer
Published in Cancer Weekly, May 11th, 2010
Scientists discuss in 'Imaging human pancreatic cancer xenografts by targeting mutant KRAS2 mRNA with [(111)In]DOTA(n)-poly(diamidopropanoyl)(m)-KRAS2 PNA-D(Cys-Ser-Lys-Cys) nanoparticles' new findings in pancreatic cancer. "95% of patients with ductal pancreatic cancer carry 12th codon activating mutations in their KRAS2 oncogenes. Early whole body imaging of mutant KRAS2 mRNA activation in pancreatic cancer would contribute to disease management," scientists in Russia report.
"Scintigraphic hybridization probes to visualize gene activity in vivo constitute a new paradigm in molecular imaging. We have previously imaged mutant KRAS2 mRNA activation in pancreatic cancer...
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Source: Cancer Weekly (2010-05-11)
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