Gastroenterology
New research on gastroenterology from Sanjay Gandhi Post Graduate Institute of Medical Sciences, Department of Medical Genetics summarized
Published in Cancer Weekly, May 25th, 2010
Investigators publish new data in the report 'Role of E-cadherin gene in gall bladder cancer and its precursor lesions.' According to recent research published in the journal Virchows Archiv, "The aim was to investigate the genomic instability in the E-cadherin (CDH1) gene and to correlate it with its protein expression in gall bladder cancer (GBC) and in other gall bladder (GB) diseases viz. chronic cholecystitis (CC), xantho-granulomatous cholecystitis (XGC), and normal GB to explicate its role in GBC tumorigenesis. Microsatellite instability (MSI) and loss of heterozygosity (LOH) in CDH1 were studied using D16S421, D16S496, D16S503, D16S512, D16S2624, and D16S3021 microsatellite...
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Source: Cancer Weekly (2010-05-25)
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