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Large B-Cell Lymphoma

Findings from Research Center in large B-cell lymphoma reported

Published in Cancer Weekly, June 1st, 2010

New investigation results, 'Inhibition of fatty acid synthase suppresses c-Met receptor kinase and induces apoptosis in diffuse large B-cell lymphoma,' are detailed in a study published in Molecular Cancer Therapeutics. According to a study from Riyadh, Saudi Arabia, "Fatty acid synthase (FASN), the enzyme responsible for de novo synthesis of fatty acids, has emerged as a potential therapeutic target for several cancers; however, its role in diffuse large B-cell lymphoma (DLBCL) has not been fully elucidated. In this study, we investigated the role of FASN in a large series of DLBCL tissues in a tissue microarray (TMA) format followed by in vitro studies using DLBCL cell...

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