Colorectal Research

Findings from Zhejiang University, Department of Pathology broaden understanding of colorectal research

Published in Cancer Weekly, June 1st, 2010

Investigators publish new data in the report 'HSP60, a protein downregulated by IGFBP7 in colorectal carcinoma.' "In our previous study, it was well defined that IGFBP7 was an important tumor suppressor gene in colorectal cancer (CRC). We aimed to uncover the downstream molecules responsible for IGFBP7's behaviour in this study," scientists in Hangzhou, People's Republic of China report.

"Differentially expressed protein profiles between PcDNA3.1(IGFBP7)-transfected RKO cells and the empty vector transfected controls were generated by two-dimensional gel electrophoresis (2-DE) and mass spectrometry (MS) identification. The selected differentially expressed protein...

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Source: Cancer Weekly (2010-06-01)

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