Primary Effusion Lymphoma
Reports outline primary effusion lymphoma study results from University of South Carolina, Hollings Cancer Center
Published in Cancer Weekly, June 1st, 2010
A new study, 'Direct activation of emmprin and associated pathogenesis by an oncogenic herpesvirus,' is now available. "Emmprin (extracellular matrix metalloproteinase inducer) is a multifunctional glycoprotein expressed by cancer cells and stromal cells in the tumor microenvironment. Through both direct effects within tumor cells and promotion of tumor-stroma interactions, emmprin induces tumor cell invasiveness and regional angiogenesis," scientists in the United States report.
"The Kaposi's sarcoma-associated herpesvirus (KSHV) is a common etiology for cancers arising in the setting of immune suppression, including Kaposi's sarcoma and primary effusion lymphoma....
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Source: Cancer Weekly (2010-06-01)
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