Hepatocellular Cancer
Reports from University of Calgary highlight recent research in hepatocellular cancer
Published in Cancer Weekly, June 15th, 2010
In this recent report, researchers in Calgary, Canada conducted a study "To compare the expression of genes involved in p53, Wnt/beta-catenin, and retinoblastoma (Rb) 1 pathways between cirrhosis-associated hepatocellular carcinoma (HCC-C) and hepatocellular carcinoma arising in non-cirrhotic liver (HCC-NC). The gene expression profile was analysed using oligo-DNA arrays, and then validated at protein level in a tissue microarray using immunohistochemistry."
"Compared with their background non-neoplastic liver tissue, HCC-C showed a significantly higher rate of p53, beta-catenin (protein only) and cyclin D1 expression, whereas HCC-NC showed a significantly higher rate...
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Source: Cancer Weekly (2010-06-15)
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